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| Product Name: |
6-bromoandrostenedione
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| Supply Ability: |
300kgs |
| Related proudcts |
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| Specifications |
ISO9001 |
| Price Term: |
FOB,CNF,CIF |
| Port of loading: |
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| Minimum Order |
1kg |
| Unit Price: |
T/T |
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6-bromoandrostenedione
Chemical Name: 6-Bromo androstane-3,17-dione
CAS#:38632-00-7
Assay: 97%
A selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione (6 alpha-BrA) is a competitive inhibitor of human placental aromatase with respect to androstenedione, with an apparent Ki of 3.4 nM, while 6 beta-BrA is a mechanism-based irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1. Aromatase activity was measured by tritium release into water from the 1 beta position of [1(-3)H,4(-14)C]androstenedione in reaction mixtures containing NADPH and the aromatase.
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| Company: |
Wuhan YuanchengTech Co.,Ltd
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| Contact: |
Mr. Steven yu |
| Address: |
496 Zhongshan Road |
| Postcode: |
430064 |
| Tel: |
86 27 88320830 |
| Fax: |
86 27 68886700 |
| E-mail: |
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